Structure-activity relationships (SAR) analysis forms the bedrock in drug discovery. By altering the chemical structure of a lead compound and measuring the resulting biological activity, researchers can elucidate the key structural features responsible for desired effects. This knowledge guides further optimization of novel therapeutic agents with

Successful drug therapy hinges upon a pharmaceutical, pharmacology profound understanding/comprehension/grasp of both pharmacodynamics and pharmacokinetics. Pharmacodynamics delves into the intricate mechanisms/processes/interactions by which drugs exert their effects on biological systems, elucidating their site of action and therapeutic outcomes.